Location: US – WI – Madison
Job Type: Full-time
Posted: 2 Days Ago
Requisition ID: R25-9797
Help Us Change Lives
At Exact Sciences, we’re revolutionizing cancer prevention, detection, and treatment. Our mission is to provide patients and clinicians with the clarity needed to make life-changing decisions. Join our inclusive, purpose-driven team and enjoy robust benefits while contributing to groundbreaking work.
Position Overview
We’re seeking a Bioinformatician II to support clinical reporting by analyzing NGS data, monitoring bioinformatics pipelines, and ensuring quality control. This role involves variant call review, assay validation, troubleshooting QC issues, and collaborating across teams to enhance pipeline efficiency. The ideal candidate has strong NGS expertise, experience in a regulated environment, and a passion for mentoring junior staff.
Key Responsibilities
✔ Implement, test, and maintain bioinformatics tools/pipelines in Python, Java, R, or MATLAB
✔ Develop automated workflows for large-scale genomic data analysis
✔ Investigate and resolve QC issues in clinical NGS data
✔ Support regulatory compliance (CAP, CLIA) and proficiency testing
✔ Optimize cloud-based (DNAnexus) and HPC workflows (WDL/Cromwell, Snakemake)
✔ Collaborate with cross-functional teams to improve bioinformatics processes
✔ Document analyses and contribute to research manuscripts/grants
Minimum Qualifications
- Bachelor’s/Master’s in Bioinformatics, CS, Computational Biology, or related field
- 2+ years of experience in NGS data analysis (academic/industry)
- Proficiency in Python, R, Linux, and shell scripting
- Experience with NGS workflows (WDL, Snakemake) and cloud platforms (DNAnexus)
- Strong understanding of statistics, variant calling, and genomic databases
- Ability to work onsite in Madison, WI (5% travel possible)
Preferred Qualifications
- Master’s/PhD in Bioinformatics, Cancer Biology, or related field
- Experience in a regulated (CLIA/CAP) environment
- Knowledge of tumor biology and variant classification
Compensation & Benefits
- Salary Range: $85,000 – $135,000 (bonus & stock eligible)
- Benefits: Medical/dental/vision, 401(k), paid time off, parental leave, wellness programs
- Culture: Inclusive, collaborative, and growth-focused
Join Our Mission
Exact Sciences is an equal opportunity employer. We value diversity and encourage all qualified applicants to apply, including those requiring accommodations.
Apply here : https://exactsciences.wd1.myworkdayjobs.com/en-GB/Exact_Sciences/job/US—WI—Madison/Bioinformatician-II—Operations_R25-9797